[1] ZHANG Siyuan, LUO Hua, SUN Shiyi, et al. Salvia miltiorrhiza Bge. (Danshen) for inflammatory bowel disease: clinical evidence and network pharmacology-based strategy for developing supplementary medical application [J/OL]. Frontiers in Pharmacology, 2022, 12: 741871[2023-11-28]. doi: 10.3389/fphar.2021.741871.
[2] 李珅, 林爱真, 杨媛, 等. 丹参酮生物合成分子调控机制的研究进展[J]. 浙江农林大学学报, 2018, 35(2): 367 − 375.

LI Shen, LIN Aizhen, YANG Yuan, et al. Research progress on molecular regulation mechanism involved in the biosynthetic pathway of tanshinone in Salvia miltiorrhiza [J]. Journal of Zhejiang A&F University, 2018, 35(2): 367 − 375.
[3]

CHEN Xiuping, GUO Jiajie, BAO Jiaolin, et al. The anticancer properties of Salvia miltiorrhiza Bunge (Danshen): a systematic review [J]. Medicinal Research Reviews, 2014, 34(4): 768 − 794.
[4]

WANG Xin, LEE W Y W, ZHOU Xuelin, et al. A pharmacodynamic-pharmacokinetic (PD-PK) study on the effects of Danshen (Salvia miltiorrhiza) on midazolam, a model CYP3A probe substrate, in the rat [J]. Phytomedicine, 2010, 17(11): 876 − 883.
[5]

ZHU Guoxue, WU Xiaoqian, JIANG Shujun, et al. The application of omics techniques to evaluate the effects of TanshinoneⅡA on dextran sodium sulfate induced ulcerative colitis [J]. Molecular Omics, 2022, 18(7): 666 − 676.
[6]

LANGE B M, RUJAN T, MARTIN W, et al. Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes [J]. Proceedings of the National Academy of Sciences of the United States of America, 2000, 97(24): 13172 − 13177.
[7]

SHI Min, ZHOU Wei, ZHANG Jianlin, et al. Methyl jasmonate induction of tanshinone biosynthesis in Salvia miltiorrhiza hairy roots is mediated by JASMONATE ZIM-DOMAIN repressor proteins [J/OL]. Scientific Reports, 2016, 6: 20919 [2023-11-28]. doi: 10.1038/srep20919.
[8]

WANG Doudou, HUANG Feifei, YAN Pengcheng, et al. Cytosolic and nucleosolic calcium-regulated molecular networks in response to long-term treatment with abscisic acid and methyl jasmonate in Arabidopsis thaliana [J/OL]. Genes, 2022, 13(3): 524[2023-11-28]. doi: 10.3390/genes13030524.
[9]

GE Xiuchun, WU Jianyong. Induction and potentiation of diterpenoid tanshinone accumulation in Salvia miltiorrhiza hairy roots by beta-aminobutyric acid [J]. Applied Microbiology and Biotechnology, 2005, 68(2): 183 − 188.
[10]

ZHOU Yangyun, SUN Wei, CHEN Junfeng, et al. SmMYC2a and SmMYC2b played similar but irreplaceable roles in regulating the biosynthesis of tanshinones and phenolic acids in Salvia miltiorrhiza [J/OL]. Scientific Reports, 2020, 10(1): 7201[2023-11-28]. doi: 10.1038/srep22852.
[11]

HAO Xiaolong, SHI Min, CUI Lijie, et al. Effects of methyl jasmonate and salicylic acid on tanshinone production and biosynthetic gene expression in transgenic Salvia miltiorrhiza hairy roots [J]. Biotechnology and Applied Biochemistry, 2015, 62(1): 24 − 31.
[12]

LI Caili, LI Dongqiao, SHAO Fenjuan, et al. Molecular cloning and expression analysis of WRKY transcription factor genes in Salvia miltiorrhiza [J/OL]. BMC Genomics, 2015, 16(1): 200[2023-11-28]. doi: 10.1186/s12864-015-1411-x.
[13]

ZHENG Han, JING Li, JIANG Xihong, et al. The ERF-Ⅶtranscription factor SmERF73 coordinately regulates tanshinone biosynthesis in response to stress elicitors in Salvia miltiorrhiza [J]. New Phytologist, 2021, 231(5): 1940 − 1955.
[14]

SHI Min, ZHU Ruiyan, ZHANG Yi, et al. A novel WRKY34-bZIP3 module regulates phenolic acid and tanshinone biosynthesis in Salvia miltiorrhiza [J]. Metabolic Engineering, 2022, 73: 182 − 191.
[15]

ZHANG Xin, LUO Hongmei, XU Zhichao, et al. Genome-wide characterisation and analysis of bHLH transcription factors related to tanshinone biosynthesis in Salvia miltiorrhiza [J]. Scientific Reports, 2015, 5(1): 11244 − 11256.
[16]

LI Caili, LU Shanfa. Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors shows the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza [J]. BMC Genomics, 2014, 15(1): 277 − 286.
[17] 王晓荣. 丹参 bHLH 类转录因子的基因克隆及功能初步研究[D]. 上海: 上海师范大学, 2015.

WANG Xiaorong. Isolation and Function Analysis of bHLH Translation Factor in Salvia miltiorrhiza [D]. Shanghai: Shanghai Normal University, 2015.
[18]

TIAN Qian, HAN Limin, ZHU Xiaoya, et al. SmMYB4 is a R2R3-MYB transcriptional repressor regulating the biosynthesis of phenolic acids and tanshinones in Salvia miltiorrhiza [J/OL]. Metabolites, 2022, 12(10): 968[2023-11-28]. doi: 10.3390/metabo12100968.
[19]

YANG Rao, WANG Shengsong, ZOU Haolin, et al. R2R3-MYB transcription factor SmMYB52 positively regulates biosynthesis of salvianolic acid B and inhibits root growth in Salvia miltiorrhiza [J/OL]. International Journal of Molecular Sciences, 2021, 22(17): 9538[2023-11-28]. doi: 10.3390/ijms22179538.
[20]

ZHANG Jianhong, LV Haizhou, LIU Wanjing, et al. bHLH transcription factor SmbHLH92 negatively regulates biosynthesis of phenolic acids and tanshinones in Salvia miltiorrhiza [J]. Chinese Herbal Medicines, 2020, 12(3): 237 − 246.
[21]

LIU Shucan, WANG Yao, SHI Min, et al. SmbHLH60 and SmMYC2 antagonistically regulate phenolic acids and anthocyanins biosynthesis in Salvia miltiorrhiza [J]. Journal of Advanced Research, 2022, 42: 205 − 219.
[22] 郭肖红, 高文远, 陈海霞, 等. 金属离子对丹参酮Ⅱ-A和原儿茶醛生物合成的影响[J]. 中国中药杂志, 2005, 30(12): 885 − 888.

GUO Xiaohong, GAO Wenyuan, CHEN Haixia, et al. Effects of mineral cations on the accumulation of tanshinone Ⅱ-A and protocatechuic aldehyde in the adventitious root culture of Salvia miltiorrhiza [J]. China Journal of Chinese Materia Medica, 2005, 30(12): 885 − 888.
[23] 张鑫, 宋经元, 胡鸢雷, 等. bHLH转录因子调控植物活性成分生物合成的研究进展[J]. 药学学报, 2014, 49(4): 435 − 442.

ZHANG Xin, SONG Jingyuan, HU Yuanlei, et al. Research progress of the regulation on active compound biosynthesis by the bHLH transcription factors in plants [J]. Acta Pharmaceutica Sinica, 2014, 49(4): 435 − 442.
[24]

CHEN Cheng, LIU Fu, ZHANG Kaixuan, et al. MeJA-responsive bHLH transcription factor LjbHLH7 regulates cyanogenic glucoside biosynthesis in Lotus japonicus [J]. Journal of Experimental Botany, 2022, 73(8): 2650 − 2665.
[25]

WANG Ning, SHU Xiaochun, ZHANG Fengjiao, et al. Transcriptome-wide characterization of bHLH transcription factor genes in Lycoris radiata and functional analysis of their response to MeJA [J/OL]. Frontiers in Plant Science, 2022, 13: 975530[2023-11-28]. doi: 10.3389/fpls.2022.975530.
[26] 李磊磊. 丹参WRKY转录因子SmWRKY54的功能初步研究[D]. 上海: 上海师范大学, 2016.

LI Leilei. The Functional Study of SmWRKY54 Transcription Factor in Salvia miltiorrhiza [D]. Shanghai: Shanghai Normal University, 2016.
[27] 孟超敏, 耿翡翡, 卿桂霞, 等. 陆地棉低磷胁迫应答基因GhGDPD1的克隆与表达分析[J]. 浙江农林大学学报, 2023, 40(4): 723 − 730.

MENG Chaomin, GENG Feifei, QING Guixia, et al. Cloning and expression analysis of low phosphorus stress response gene GhGDPD1 in Gossypium hirsutum [J]. Journal of Zhejiang A&F University, 2023, 40(4): 723 − 730.
[28] 卓娟, 侯丹, 林新春. 毛竹PhebHLH6基因克隆及表达分析[J]. 浙江农林大学学报, 2023, 40(4): 731 − 737.

ZHUO Juan, HOU Dan, LIN Xinchun. Cloning and expression analysis of PhebHLH6 gene from Phyllostachys edulis [J]. Journal of Zhejiang A&F University, 2023, 40(4): 731 − 737.
[29]

LI Lin, WANG Donghao, ZHOU Li, et al. JA-responsive transcription factor SmMYB97 promotes phenolic acid and tanshinone accumulation in Salvia miltiorrhiza [J]. Journal of Agricultural and Food Chemistry, 2020, 68(50): 14850 − 14862.
[30]

SASAKI-SEKIMOTO Y, JIKUMARU Y, OBAYASHI T, et al. Basic helix-loop-helix transcription factors JASMONATE-ASSOCIATED MYC2-LIKE1 (JAM1), JAM2, and JAM3 are negative regulators of jasmonate responses in Arabidopsis [J]. Plant Physiology, 2013, 163(1): 291 − 304.
[31]

NAKATA M, OHME-TAKAGI M. Two bHLH-type transcription factors, JA-ASSOCIATED MYC2-LIKE2 and JAM3, are transcriptional repressors and affect male fertility [J/OL]. Plant Signaling and Behavior, 2013, 8(12): e26473[2023-11-28]. doi: 10.4161/psb.26473.
[32]

YANG Na, ZHOU Wenping, SU Jiao, et al. Overexpression of SmMYC2 increases the production of phenolic acids in Salvia miltiorrhiza [J/OL]. Frontiers in Plant Science, 2017, 8: 1804[2023-11-28]. doi: 10.3389/fpls.2017.01804.
[33]

ZHAO Shujuan, ZHANG Jinjia, TAN Ronghui, et al. Enhancing diterpenoid concentration in Salvia miltiorrhiza hairy roots through pathway engineering with maize C1 transcription factor [J]. Journal of Experimental Botany, 2015, 66(22): 7211 − 7126.
[34]

HE Kunrong, DU Jiancan, HAN Xiao, et al. PHOSPHATE STARVATION RESPONSE1 (PHR1) interacts with JASMONATE ZIM-DOMAIN (JAZ) and MYC2 to modulate phosphate deficiency-induced jasmonate signaling in Arabidopsis [J]. The Plant Cell, 2023, 35(6): 2132 − 2156.
[35]

ZHUO Mengna, SAKURABA Y, YANAGISAWA S. A jasmonate-activated MYC2-Dof2.1-MYC2 transcriptional loop promotes leaf senescence in Arabidopsis [J]. The Plant Cell, 2020, 32(1): 242 − 262.
[36]

DENG Huaiyu, LI Qi, CAO Ruizhi, et al. Overexpression of SmMYC2 enhances salt resistance in Arabidopsis thaliana and Salvia miltiorrhiza hairy roots [J/OL]. Journal of Plant Physiology, 2023, 280: 153862 [2023-11-28]. doi: 10.1016/j.jplph.2022.153862.
[37] 汪琬宜, 蒋喜红, 张利华, 等. 丹参转录因子SmbHLH1基因的克隆和表达分析[J]. 中国中药杂志, 2011, 36(24): 3416 − 3420.

WANG Wanyi, JIANG Xihong, ZHANG Lihua, et al. Isolation and characteristics of SmbHLH1 gene in Salvia miltiorrhiza [J]. China Journal of Chinese Materia Medica, 2011, 36(24): 3416 − 3420.
[38]

ZHOU Wei, WANG Shuai, SHEN Yafang, et al. Overexpression of SmSCR1 promotes tanshinone accumulation and hairy root growth in Salvia miltiorrhiza [J/OL]. Frontiers in Plant Science, 2023, 13: 860033 [2023-11-28]. doi: 10.3389/fpls.2022.860033.
[39]

ZHOU Wei, SHI Min, DENG Changping, et al. The methyl jasmonate-responsive transcription factor SmMYB1 promotes phenolic acid biosynthesis in Salvia miltiorrhiza [J/OL]. Horticulture Research, 2021, 8(1): 10 [2023-11-28]. doi: 10.1038/s41438-020-00443-5.
[40]

ZHOU Wei, HUANG Qiang, WU Xiao, et al. Comprehensive transcriptome profiling of Salvia miltiorrhiza for discovery of genes associated with the biosynthesis of tanshinones and phenolic acids [J/OL]. Scientific Reports, 2017, 7(1): 10554 [2023-11-28]. doi: 10.1038/s41598-017-10215-2.