Radioprotective effects of extract from <em>Carya cathayensis</em> nut exocarp on mice

YANG Qiong-xia; YIN Shu; SHENTU Yin; GAO Xin; SUN Yi; HU Jun-xiang

Volume 23 Issue 6

Feb. 2017

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YANG Qiong-xia, YIN Shu, SHENTU Yin, GAO Xin, SUN Yi, HU Jun-xiang. Radioprotective effects of extract from Carya cathayensis nut exocarp on mice[J]. Journal of Zhejiang A&F University, 2006, 23(6): 604-607.

Citation:

YANG Qiong-xia, YIN Shu, SHENTU Yin, GAO Xin, SUN Yi, HU Jun-xiang. Radioprotective effects of extract from Carya cathayensis nut exocarp on mice[J]. Journal of Zhejiang A&F University, 2006, 23(6): 604-607.

Radioprotective effects of extract from Carya cathayensis nut exocarp on mice

1.
School of Forestry and Biotechnology , Zhejiang Forestry College , Lin'an 311300, Zhejiang , China;
2.
.College of Life Sciences, Zhejiang University , Hangzhou 310012, Zhejiang , China

Publish Date: 2006-12-20

Abstract

Radioprotective effects of the extract from hickory (Carya cathayensis) nut exocarp on NIH mice which were radiated by ray were studied .Subject mice were randomly divided into five groups :negative control group , radiation group and three medicine groups which were given extract of different dosage .Except negative control group , all the other groups were exposed to 60 Co ray ;all mice were killed in five days .Body weight , index of hemogram, content of malondialdehyde (MDA) and vitality of superoxide dismutase (SOD) were tested respe ctively .The results indicated that compared with negative control group , radiation groups quantity of periphery blood leucocyte , red blood corpuscles , blood platelet , hemoglobin and hematocrit significantly lowered (P 0.05), and the corresponding indexes of medicine groups given extract of different dosage increased .The content of MDA in serum and liver tissue of radiation group was notably higher than negative control group (P 0.05), compared with radiation group , the content of MDA of medicine groups remarkably reduced with the increase of extract dosage (P 0.05).The vitality of SOD in serum and liver of radiation group was notably lower than negative control group (P 0.05), compared with radiation group , the vitality of SOD of medicine groups increased and had certain dosage effect .The results suggested that the extract had good radioprotective effects on the oxidation damage caused by radiation .[ Ch , 2 tab .7 ref .]
- zoology,
- Carya cathayensis,
- exocarp extract,
- Mus musculus,
- radioprotection,
- malondialdehyde(MDA),
- superoxide dismutase (SOD)

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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Radioprotective effects of extract from Carya cathayensis nut exocarp on mice

1. School of Forestry and Biotechnology , Zhejiang Forestry College , Lin'an 311300, Zhejiang , China;

2. .College of Life Sciences, Zhejiang University , Hangzhou 310012, Zhejiang , China

Publish Date: 2006-12-20

Key words:

Abstract: Radioprotective effects of the extract from hickory (Carya cathayensis) nut exocarp on NIH mice which were radiated by ray were studied .Subject mice were randomly divided into five groups :negative control group , radiation group and three medicine groups which were given extract of different dosage .Except negative control group , all the other groups were exposed to 60 Co ray ;all mice were killed in five days .Body weight , index of hemogram, content of malondialdehyde (MDA) and vitality of superoxide dismutase (SOD) were tested respe ctively .The results indicated that compared with negative control group , radiation groups quantity of periphery blood leucocyte , red blood corpuscles , blood platelet , hemoglobin and hematocrit significantly lowered (P 0.05), and the corresponding indexes of medicine groups given extract of different dosage increased .The content of MDA in serum and liver tissue of radiation group was notably higher than negative control group (P 0.05), compared with radiation group , the content of MDA of medicine groups remarkably reduced with the increase of extract dosage (P 0.05).The vitality of SOD in serum and liver of radiation group was notably lower than negative control group (P 0.05), compared with radiation group , the vitality of SOD of medicine groups increased and had certain dosage effect .The results suggested that the extract had good radioprotective effects on the oxidation damage caused by radiation .[ Ch , 2 tab .7 ref .]

Radioprotective effects of extract from Carya cathayensis nut exocarp on mice

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Radioprotective effects of extract from Carya cathayensis nut exocarp on mice

1. School of Forestry and Biotechnology , Zhejiang Forestry College , Lin'an 311300, Zhejiang , China;

2. .College of Life Sciences, Zhejiang University , Hangzhou 310012, Zhejiang , China

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Radioprotective effects of extract from Carya cathayensis nut exocarp on mice

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Radioprotective effects of extract from Carya cathayensis nut exocarp on mice

1. School of Forestry and Biotechnology , Zhejiang Forestry College , Lin'an 311300, Zhejiang , China; 2. .College of Life Sciences, Zhejiang University , Hangzhou 310012, Zhejiang , China

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1. School of Forestry and Biotechnology , Zhejiang Forestry College , Lin'an 311300, Zhejiang , China;

2. .College of Life Sciences, Zhejiang University , Hangzhou 310012, Zhejiang , China